Edit |   |
Antigenic Specificity | Phospho-c-Jun (Ser63) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-c-Jun (Ser63) antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 63. Description: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression.Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds t |
Immunogen | Immunogen: A synthesized peptide derived from human c-Jun around the phosphorylation site of Serine 63 Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (91%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (82%), Xenopus (82%) |
Other Names | [Activator protein 1; AP 1; AP1; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN; Jun oncogene; JUN protein; Jun proto oncogene; JUN_HUMAN; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription factor AP-1; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian); V jun sarcoma virus 17 oncogene homolog; V-jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog] |
Gene, Accession # | [JUN], Gene ID: 3725, NCBI: NP_002219.1, UniProt: P05412 |
Catalog # | MBS9600861 |
Price | $240, $280 |
Order / More Info | Phospho-c-Jun (Ser63) Antibody from MYBIOSOURCE INC. |
Product Specific References | Wu Z, Wang T, Fang M, Huang W, Sun Z, Xiao J, Yan W; Journal: Biochem Biophys Res Commun. MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer. |