IRAK1 (C-term) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IRAK1 (C-term) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IRAK1 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IRAK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 608-639 amino acids from the C-terminal region of human IRAK1. Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor- signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO b |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Interleukin-1 receptor-associated kinase 1; IRAK-1; IRAK1; IRAK] |
| Gene, Accession # | [IRAK1], Gene ID: 3654, NCBI: NP_001020413.1, UniProt: P51617 |
| Catalog # | MBS9216431 |
| Price | $150 |
| Order / More Info | IRAK1 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cao Z.,et al.Science 271:1128-1131(1996). Reichwald K.,et al.Mamm. Genome 11:182-190(2000). Jensen L.E.,et al.J. Biol. Chem. 276:29037-29044(2001).Rao N.,et al.Mol. Cell. Biol. 25:6521-6532(2005). Ross M.T.,et al.Nature 434:325-337(2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies