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Antigenic Specificity | TALIN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TALIN1 antibody detects endogenous levels of TALIN1. Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).Subunit Structure: Binds with high affinity to VCL and with low affinity to integrins (PubMed:15070891). Interacts with APBB1IP; this inhibits VCL binding. Interacts with PTK2/FAK1 (By similarity). Interacts with PIP5K1C and NRAP (PubMed:10320340, PubMed:12422220). Interacts with LAYN (By similarity). Interacts with SYNM (PubMed:18342854). Interacts with ITGB1; the interaction is prevented by competitive binding of ITGB1BP1 |
Immunogen | Immunogen: A synthesized peptide derived from human TALIN1 Subcellular Location: Cell Projection, Ruffle Membrane. Cytoplasm, Cytoskeleton. Cell Surface. Cell Junction, Focal Adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity). |
Other Names | [ILWEQ; Talin 1; Talin; Talin-1; TLN 1; TLN; Tln1; TLN1_HUMAN] |
Gene, Accession # | [TALIN1], Gene ID: 7094, NCBI: NP_006280.3, UniProt: Q9Y490 |
Catalog # | MBS9603226 |
Price | $240, $280 |
Order / More Info | TALIN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |