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Antigenic Specificity | GABA (A) a1 Receptor (Extracellular) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake, and metabolism all occur in the nervous system.1 The GABA transmitter interacts with two major types of receptors: ionotropic GABAA receptors (GABAAR) and metabotropic receptors (GABABR). GABAARs belong to the ligand-gated ion channel superfamily.2 GABA inhibits the activity of signal-receiving neurons by interacting with the GABAA receptor on these cells.3 Binding of GABA to its GABAA receptor results in conformational changes that open a Cl-channel, producing an increase in membrane conductance that results in inhibition of neural activity.2 GABAARs are heteropentamers, in which all five subunits contribute to pore formatio |
Immunogen | Immunogen: Peptide QPSQD ELKDN TTVFT R(C), corresponding to amino acid residues 28-43 of rat GABA(A) beta1 (AccessionP18504). |
Other Names | [GABAA Receptor (alpha1 subunit)] |
Gene, Accession # | n/a |
Catalog # | MBS4157611 |
Price | $725 |
Order / More Info | GABA (A) a1 Receptor (Extracellular) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |