GABA (A) a1 Receptor (Extracellular) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGABA (A) a1 Receptor (Extracellular)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatantigen affinity purified
Size0.05 mL
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionGABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake, and metabolism all occur in the nervous system.1 The GABA transmitter interacts with two major types of receptors: ionotropic GABAA receptors (GABAAR) and metabotropic receptors (GABABR). GABAARs belong to the ligand-gated ion channel superfamily.2 GABA inhibits the activity of signal-receiving neurons by interacting with the GABAA receptor on these cells.3 Binding of GABA to its GABAA receptor results in conformational changes that open a Cl-channel, producing an increase in membrane conductance that results in inhibition of neural activity.2 GABAARs are heteropentamers, in which all five subunits contribute to pore formatio
ImmunogenImmunogen: Peptide QPSQD ELKDN TTVFT R(C), corresponding to amino acid residues 28-43 of rat GABA(A) beta1 (AccessionP18504).
Other Names[GABAA Receptor (alpha1 subunit)]
Gene, Accession #n/a
Catalog #MBS4157611
Price$725
Order / More InfoGABA (A) a1 Receptor (Extracellular) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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