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Antigenic Specificity | Rab5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey, bovine |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Rab5 is a 24 kDa GTP-binding protein that is localized to the cytoplasmic side of the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5 is believed to regulate vesicle fusion thromugh a cycle of GDP/GTP exchange and GTP hydrolysis. The different guanine nucleotide binding states of rab5 is postulated to affect its ability to associate or dissociate with membranes during endocytotic membrane traffic. Its GTP-bound form, which represents the active form of Rab5, associates with membrane and regulates vesicle docking and fusion. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 185 of human Rab5 |
Other Names | [RAB5; Rab5a; RAS; RAS associated protein; RAB5A; RAB 5A; RAB 5], [RAB5A; RAB5A; RAB5; RAB5] |
Gene, Accession # | [Rab5], Gene ID: 5868, NCBI: NP_001278977.1, UniProt: P20339 |
Catalog # | MBS840388 |
Price | $150, $305 |
Order / More Info | Rab5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |