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Antigenic Specificity | Phospho-NMDAR2A (Tyr943) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, sheep |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-NMDAR2A (Tyr943) Antibody detects endogenous levels of NMDAR2A only when phosphorylated at Tyr943. Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:8768735, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinet |
Immunogen | Immunogen: A synthesized peptide derived from human NMDAR2A around the phosphorylation site of Tyr943. |
Other Names | [GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A; hNR3; N methyl D aspartate receptor subtype 2A; N methyl D aspartate receptor subtype 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2A; NMDAR2B; NMDE1_HUMAN; NR2A; NR2B; NR3] |
Gene, Accession # | [NMDAR2A], Gene ID: 2903, NCBI: NP_000824.1, UniProt: Q12879 |
Catalog # | MBS9610724 |
Price | $225, $280, $340 |
Order / More Info | Phospho-NMDAR2A (Tyr943) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |