Phospho-NMDAR2A (Tyr943) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-NMDAR2A (Tyr943)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, sheep
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-NMDAR2A (Tyr943) Antibody detects endogenous levels of NMDAR2A only when phosphorylated at Tyr943. Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:8768735, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinet
ImmunogenImmunogen: A synthesized peptide derived from human NMDAR2A around the phosphorylation site of Tyr943.
Other Names[GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A; hNR3; N methyl D aspartate receptor subtype 2A; N methyl D aspartate receptor subtype 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2A; NMDAR2B; NMDE1_HUMAN; NR2A; NR2B; NR3]
Gene, Accession #[NMDAR2A], Gene ID: 2903, NCBI: NP_000824.1, UniProt: Q12879
Catalog #MBS9610724
Price$225, $280, $340
Order / More InfoPhospho-NMDAR2A (Tyr943) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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