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Antigenic Specificity | HNF1A (Pancreatic Tumor Suppressor) |
Clone | [HNF1A/2087] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet beta cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer. |
Immunogen | Immunogen: Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary) Positive Control: Jurkat Cells. Small Intestine or Pancreas |
Other Names | [Albumin proximal factor; Hepatic nuclear factor 1 alpha; Hepatic transcription factor 1 alpha; HNF-1A; Interferon production regulator factor; LFB1; LFB1 hepatic nuclear factor; Liver specific transcription factor LFB1; Maturity onset diabetes of the young 3 (MODY3); TCF1; Transcription factor 1 hepatic] |
Gene, Accession # | [HNF1A], Gene ID: 6927, NCBI: NP_000536.5, UniProt: P20823 |
Catalog # | MBS4380701 |
Price | $190, $340, $340 |
Order / More Info | HNF1A (Pancreatic Tumor Suppressor) Antibody from MYBIOSOURCE INC. |
Product Specific References | Bach, I., et al. 1993. EMBO J. 12: 4229-4242. |