CTCFL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTCFL
Clone[65]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatcaprylic acid ammonium sulfate precipitate
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunofluorescence (IF), ELISA (EIA)
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DescriptionCTCFL, also named BORIS (for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
ImmunogenImmunogen: Fusion protein of BORIS
Other Names[BORIS like protein; Brother of the regulator of imprinted sites; Cancer/testis antigen 27; CCCTC binding factor (zinc finger protein) like; CCCTC-binding factor; CT27; CTCF paralog; CTCF T; CTCF-like protein; Ctcfl; CTCFL; dJ579F20.2; HMG 1L1; HMGB1L1; MGC163358; MGC169105; MGC169106; Putative high mobility group protein 1 like 1; Putative high mobility group protein B1 like 1; Transcriptional repressor CTCFL; Zinc finger protein CTCF-T]
Gene, Accession #[CTCFL], Gene ID: 140690, NCBI: NP_001255969.1, UniProt: Q8NI51
Catalog #MBS2542130
Price$220, $290, $435
Order / More InfoCTCFL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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