Edit |   |
Antigenic Specificity | Bax (Apoptosis Marker) |
Clone | [SPM336] |
Host Species | Mouse |
Reactive Species | human, monkey. does not react with mouse and rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. |
Immunogen | Immunogen: A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. |
Other Names | [Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812 |
Catalog # | MBS438080 |
Price | $190, $340, $340 |
Order / More Info | Bax (Apoptosis Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hsu YT, et. al. Journal of Biological Chemistry, 1997, 272(21):13829-34. Hsu YT, et. al. PNAS, 1997, 94(8):3668-72. Wolter KG, et. al. Journal of Cell Biology, 1997, 139(5):1281-92 |