Bax (Apoptosis Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBax (Apoptosis Marker)
Clone[SPM336]
Host SpeciesMouse
Reactive Specieshuman, monkey. does not react with mouse and rat
IsotypeIgG1
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
ImmunogenImmunogen: A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Other Names[Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4]
Gene, Accession #[BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812
Catalog #MBS438080
Price$190, $340, $340
Order / More InfoBax (Apoptosis Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHsu YT, et. al. Journal of Biological Chemistry, 1997, 272(21):13829-34. Hsu YT, et. al. PNAS, 1997, 94(8):3668-72. Wolter KG, et. al. Journal of Cell Biology, 1997, 139(5):1281-92
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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