CaMKII (Alpha-Specific) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CaMKII (Alpha-Specific) |
| Clone | [6G9] |
| Host Species | Mouse |
| Reactive Species | mouse, rat, bovine, human |
| Isotype | IgG1 kappa |
| Format | PerCP conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC), Radioimmunoassay (RIA), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~50-60kDa protein, corresponding to the molecular mass of CaMKII alpha-subunit on SDS page immunoblots. Recognizes both phosphorylated and non-phosphorylated forms. Scientific Background: CaMKII is an important member of the calcium/calmodulin-activated protein kinase family, functioning in neural synaptic stimulation and T-cell receptor signaling (1, 2). CaMKII is expressed in many different tissues but is specifically found in the neurons of the forebrain and its mRNA is found within the dendrites and the soma of the neuron. The CaMKII that is found in the neurons consist of two subunits of 52 (termed alpha genes) and 60 kDa (beta genes). CaMKII has catalytic and regulatory domains, as well as an ATP-binding domai |
| Immunogen | n/a |
| Other Names | [CamK2; CamK2A; CamK2B; CamK2D; CamK2G; CAMKA], [Camk2a; Camk2a; CaMKII; R74975; mKIAA0968; CaM kinase II subunit alpha; CaMK-II subunit alpha] |
| Gene, Accession # | Gene ID: 12322, NCBI: NP_033922.1, UniProt: P11798 |
| Catalog # | MBS800129 |
| Price | $415 |
| Order / More Info | CaMKII (Alpha-Specific) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hughes K. et al. (2001) J. Biol. Chem. 276: 36008-36013. 2. Barria A. et al. (1997) Science 276: 2042-2045. 3. Bennet M.K. and Kennedy M.B. (1987) Proc. Natl. Acad. Sci. U.S.A. 84: 1794-1798. 4. Broke L., Srinivasan M. and Schulman H. (1995) J. Neurosci. 15: 6797-6808. 5. Nghiem P., Saati S. M., Martens C. L., Gardner P. and Schulman H. (1993) J. Biol. Chem. 268: 5471-5479. 6. Edman C.F. and Schulman H. (1994) Biochem. Biophys. Acta 1221: 90-102. 7. Tombes R.M. and Krystal G.W., (1997) Biochem. Biophys. Acta 13555: 281-292. 8. Means A.R. (2000) Mol. Endocrinol. 14: 4-12. 9. Makhinson M. et al. (1999) J. Neurosci. 19: 2500-2510. 10. Strack S. and Colbran R.J. (1998) J. Biol. Chem. 273: 20689-20692. 11. Leonard S.A., Lim I.A., Hemsworth D.E., Horne M.C. and Hell J.W. (1999) Proc. Natl. Acad. Sci. U.S.A. 96: 3239-3244. 12. Shen K. and Meyer Y. (1999) Science 284: 162-167.1. Feng, T., Szabo, E., Dziak, E. and Opas, M. (2010). Cytoskeletal disassembly and cell rounding promotes adipogenesis from ES cells. Stem Cell Rev. 6 (1), 74-85. doi: 10.1007/s12015-010-9115-8. |
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MYBIOSOURCE INC.
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