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Antigenic Specificity | RAB17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane |
Immunogen | Immunogen: Recombinant human Ras-related protein Rab-17 protein (1-212AA) |
Other Names | [Ras-related protein Rab-17; RAB17] |
Gene, Accession # | [RAB17], Gene ID: 64284, NCBI: NP_071894.1, UniProt: Q9H0T7 |
Catalog # | MBS7045151 |
Price | $120, $160 |
Order / More Info | RAB17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |