TorsinA Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TorsinA antibody, protein, ELISA kits.
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| Antigenic Specificity | TorsinA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human TorsinA. The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5). |
| Immunogen | Immunogen: A synthetic -peptide of human TorsinA |
| Other Names | [TOR1A; TorsinA; TorsinA; TOR1A, DQ2, DYT1, Torsin-1A, Dystonia 1 protein, Torsin family 1 member A], [TOR1A; TOR1A; DQ2; DYT1; DQ2; DYT1] |
| Gene, Accession # | Gene ID: 1861, NCBI: NP_000104.1, UniProt: O14656 |
| Catalog # | MBS125727 |
| Price | $275, $430 |
| Order / More Info | TorsinA Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fahn, S. (1988) Adv. Neurol. 50, 1-8. 2. Ozelius, L.J. et al. (1997) Nat. Genet. 17, 40-8. 3. Caldwell, G.A. et al. (2003) Hum. Mol. Genet. 12, 307-19. 4. McLean, P.J. et al. (2002) J. Neurochem. 83, 846-54. 5. O'Farrell, C. et al. (2004) Brain Res. Mol. Brain Res. 127, 1-9. |
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MYBIOSOURCE INC.
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