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Antigenic Specificity | FoxA2(HNF3beta) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total FoxA2(HNF3b) protein. Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at l |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.435~439(A-S-P-L-A) derived from Human FoxA2(HNF3b). |
Other Names | [FoxA2(HNF3b); HNF3B; TCF3B] |
Gene, Accession # | [FoxA2], Gene ID: 3170, NCBI: NP_068556.2, UniProt: Q9Y261 |
Catalog # | MBS9403917 |
Price | $200, $255 |
Order / More Info | FoxA2(HNF3beta) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |