FoxA2(HNF3beta) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFoxA2(HNF3beta)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total FoxA2(HNF3b) protein. Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at l
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.435~439(A-S-P-L-A) derived from Human FoxA2(HNF3b).
Other Names[FoxA2(HNF3b); HNF3B; TCF3B]
Gene, Accession #[FoxA2], Gene ID: 3170, NCBI: NP_068556.2, UniProt: Q9Y261
Catalog #MBS9403917
Price$200, $255
Order / More InfoFoxA2(HNF3beta) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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