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Antigenic Specificity | HIST1H2BA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.98mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination, acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues. Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts. |
Immunogen | Immunogen: Synthetic peptide of human HIST1H2BA |
Other Names | [HIST1H2BA; Testis; BA317E16.3; H2B; H2B histone family member U; H2B histone family member U testis specific; H2B histone family; Member U,(testis specific); H2B testis; H2B1A; H2BFU; H2BT; HIST1H2BA; Histone 1; H2ba; Histone cluster 1 H2ba; Histone H2B; Histone H2B testis; Histone H2B type 1 A; Histone H2B type 1-A; Histone H2B type 1A; STBP; Testis specific histone H2B; Testis-specific histone H2B; TSH 2B; TSH2B; TSH2B.1] |
Gene, Accession # | [HIST1H2BA], Gene ID: 255626, NCBI: NP_733759.1, UniProt: Q96A08 |
Catalog # | MBS2561673 |
Price | $110, $150, $225 |
Order / More Info | HIST1H2BA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |