PDGFR-B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDGFR-B
Clone[RBT-PDGFRB]
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate)
Concentrationn/a
Applicationsn/a
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DescriptionBeta-type Platelet-Derived Growth Factor Receptor is a protein that in humans is encoded by the PDGFRB gene. This gene encodes a cell surface tyrosine kinase receptor for members of the Platelet-Derived Growth Factor family (PDGF), which is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. Translocation of the PDGFR gene with the Tel gene is linked to Chronic Myelomonocytic Leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myel
ImmunogenImmunogen: Highly pure (>98%) recombinant hPDGF-B (human Platelet Derived Growth Factor). Localization: Cytoplasmic, Membranous. Reactivity: Paraffin, Frozen. Control: Brain, Testis, Breast, Colon, Fallopian Tube
Other Namesn/a
Gene, Accession #[PDGFR-B], NCBI: AFV92359.1
Catalog #MBS373051
Price$130, $290, $315
Order / More InfoPDGFR-B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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