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Antigenic Specificity | Caspase-10/FLICE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The current dogma of apoptosis suggests that the components of the core cell-death machinery are integral to cells and widely conserved across species. Caspases are typically divided into 3 major groups, depending on the structure of their prodomain and their function. Group 1: inflammatory caspases (caspases 1, 4, 5, 11, 12, 14). Group II: initiator of apoptosis caspases (caspases 2, 8, 9). Group III: effector caspases (caspases 3, 6, 7). Caspases are constitutively expressed in almost all cell types as inactive proenzymes (zymogens: enzyme precursors which require a biochemical change to become active enzymes) that are processed and activated in response to a variety of pro-apoptotic or inflammatory stimuli. The procaspases (32-56 kDa) co |
Immunogen | Immunogen Information: A recombinant full-length human Caspase-10/FLICE2 protein was used as the immunogen for this antibody |
Other Names | [CASP10; MCH4; Apoptotic protease Mch-4; FLICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; ICE-like apoptotic protease 4; to Caspase-10/FLICE2; Caspase-10/FLICE2; Caspase-10/FLICE2], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: Q92851.3, UniProt: Q92851 |
Catalog # | MBS668569 |
Price | $270 |
Order / More Info | Caspase-10/FLICE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |