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Antigenic Specificity | Artn |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Artn. ARTN encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor gro |
Immunogen | Immunogen: Synthesized peptide derived from part region of human Artn protein at amino acid sequence of 101-150 |
Other Names | [Rabbit Artn; Artemin; Enovin; Neublastin] |
Gene, Accession # | [ARTN], Gene ID: 9048, NCBI: AAD13110.1, UniProt: Q5T4W7 |
Catalog # | MBS9708418 |
Price | $130, $220, $325 |
Order / More Info | Artn Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |