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Antigenic Specificity | ATG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Candida glabrata |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 |
Immunogen | Immunogen: Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein |
Other Names | [Serine/threonine-protein kinase ATG1; Autophagy-related protein 1; ATG1] |
Gene, Accession # | [ATG1], Gene ID: 2890744, NCBI: XP_449036.1, UniProt: Q6FL58 |
Catalog # | MBS7000392 |
Price | $160, $235 |
Order / More Info | ATG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |