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Antigenic Specificity | Talin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein. TLN1 encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The talin 1 plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Talin-1 |
Other Names | [Rabbit Talin-1; KIAA1027; TLN; Talin-1] |
Gene, Accession # | [TLN1], Gene ID: 7094, NCBI: AAF23322.1, UniProt: Q9Y490 |
Catalog # | MBS9703952 |
Price | $130, $220, $325 |
Order / More Info | Talin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |