SHANK1 / SHANK3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SHANK1 / SHANK3 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human, mouse, and rat SHANK1/SHANK3. SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development. |
| Immunogen | Immunogen: Fusion protein corresponding to aa 538-626 (SH3 domain) of rat SHANK3. This sequence is 100% identical in mouse, 97% identical in human, and ~70% identical in SHANK1 and SHANK2. |
| Other Names | [SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains 3; Proline-rich synapse-associated protein 2; ProSAP2; SPANK-2], [Shank3; Shank3; Prosap2; Prosap2; Shank3; ProSAP2] |
| Gene, Accession # | [SHANK1/SHANK3], Gene ID: 59312, NCBI: NP_067708.1, UniProt: Q9JLU4 |
| Catalog # | MBS191362 |
| Price | $410 |
| Order / More Info | SHANK1 / SHANK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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