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Antigenic Specificity | Mouse CD8alpha/Lyt-2 |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha chain of the murine CD8 heterodimer, Mr 32-34 kDa. In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an alpha chain (CD8alpha) and a beta chain (CD8beta); and (ii) a homodimer of two alpha chains. The heterodimer is found on the surface of essentially all thymocytes and the-suppressor/cytotoxic-subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8alpha without CD8beta. It has been suggested that CD8+beta-T cells mature extrathymically, while development of the CD8alpha+beta+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restric |
Immunogen | n/a |
Other Names | [CD8alpha-Lyt-2] |
Gene, Accession # | [CD8alpha/Lyt-2] |
Catalog # | MBS4151580 |
Price | $445 |
Order / More Info | Mouse CD8alpha/Lyt-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |