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Antigenic Specificity | Human IL-10 receptor alpha |
Clone | [7Q35] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-10 Ra extracellular domain. |
Other Names | [IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1], [IL10RA; IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1] |
Gene, Accession # | [IL-10 receptor alpha], Gene ID: 3587, NCBI: NP_001549.2, UniProt: Q13651 |
Catalog # | MBS690910 |
Price | $490 |
Order / More Info | Human IL-10 receptor alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |