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Antigenic Specificity | Cav beta 4 |
Clone | [S10-7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, hamster |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Antibody Microarray (AM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~50 kDa. No cross-reactivity against rat Cab Beta1b, Cav beta2a, and Cav betas3 in transfected cells. This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting a |
Immunogen | Immunogen: Synthetic peptide amino acids 458-474 of rat CavB4 |
Other Names | [Mouse Rat Cav beta 4 IgG1; Cav beta 4 : APC/Cy7; CAB4; CACNLB4; EA5; EJM; Calcium channel voltage dependent beta 4 subunit] |
Gene, Accession # | [CACNB4], Gene ID: 785, NCBI: NP_000717, UniProt: O00305 |
Catalog # | MBS8002866 |
Price | $510 |
Order / More Info | Cav beta 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: CACNB4 calcium channel, voltage-dependent, beta 4 subunit. 2. Xie M., et al. (2007) J Cell Biol. 178(3): 489-502. |