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Antigenic Specificity | Trx-Tag |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkappaB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. Thioredoxin 2 (Trx-2) is a small redox pro |
Immunogen | Immunogen: Recombinant protein of Trx tag |
Other Names | n/a |
Gene, Accession # | [TRX-Tag] |
Catalog # | MBS126162 |
Price | $230, $350 |
Order / More Info | Trx-Tag Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |