Piccolo Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPiccolo
Clone[6H9-B6]
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG2b
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA; Immunoblot
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DescriptionSpecificity: Piccolo. This antibody recognizes human and rat Piccolo isoforms (other species not yet tested). It does not cross-react with Bassoon. Piccolo is a novel component of the presynaptic cytoskeletal matrix (PCM) assembled at the active zone of neurotransmitter release. Piccolo is a multidomain zinc finger protein structurally related to Bassoon, another PCM protein. Both proteins share components of glutamatergic and GABAergic CNS synapses. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/Synaptobrevin II receptor PRA1. Piccolo is involved in endo- and exocytosis of synaptic vesicles and has been shown to interfere with clathrin-mediated endocytosis by binding to the F-actin and dynamin bind protein Abp1.
ImmunogenAntigen: Full-length human Piccolo protein (accession no. BC001304.1)
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS190592
Price$365
Order / More InfoPiccolo Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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