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Antigenic Specificity | HTR1A (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regu |
Immunogen | n/a |
Other Names | [5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; G-21; Serotonin receptor 1A; HTR1A; ADRB2RL1; ADRBRL1] |
Gene, Accession # | [HTR1A], Gene ID: 3350, NCBI: NP_000515.2, UniProt: P08908 |
Catalog # | MBS9203992 |
Price | $165, $370 |
Order / More Info | HTR1A (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kobilka B.K.,et al.Nature 329:75-79(1987). Saltzman A.G.,et al.Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases. Levy F.O.,et al.Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases. Kitano T.,et al.Mol. Biol. Evol. 21:936-944(2004). Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. |