Mouse CASP3 (N-term S12) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CASP3 (N-term S12)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis mouse CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse CASP3. Description: CASP3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory proces
Immunogenn/a
Other Names[Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; LICE; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; Casp3; Cpp32]
Gene, Accession #[Casp3], Gene ID: 12367, NCBI: NP_033940.1, UniProt: P70677
Catalog #MBS9217101
Price$165, $370
Order / More InfoMouse CASP3 (N-term S12) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSrikanth, C.V., et al. Science 330 (6002):390-393 (2010). Li, F., et al. Cell Stem Cell 7 (4):508-520 (2010). Wang, L., et al. J. Neurosci. 30 (39):13201-13210 (2010). Gascon, E., et al. J. Neurosci. 30 (37):12414-12423 (2010). Bohsali, A., et al. BMC Microbiol. 10, 237 (2010).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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