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Antigenic Specificity | Human 5-hydroxytryptamine receptor 2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytry |
Immunogen | Immunogen: Recombinant human 5-hydroxytryptamine receptor 2B protein (382-481aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15076 / sc-15080 / sc-25647 |
Other Names | [5-HT-2B; 5-HT2B; Serotonin receptor 2B; HTR2B], [HTR2B; HTR2B; 5-HT2B; 5-HT(2B); 5-HT-2B; 5-HT2B] |
Gene, Accession # | [PTGES3], Gene ID: 3357, NCBI: NP_000858.3, UniProt: P41595 |
Catalog # | MBS1499219 |
Price | $120, $160 |
Order / More Info | Human 5-hydroxytryptamine receptor 2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |