Mouse Stk4 (C-term), 443-470 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Stk4 (C-term), 443-470
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse Stk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-470 amino acids from the C-terminal region of mouse Stk4. Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates a
Immunogenn/a
Other Names[Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase 1; MST-1; STE20-like kinase MST1; Serine/threonine-protein kinase 4 37kDa subunit; MST1/N; Serine/threonine-protein kinase 4 18kDa subunit; MST1/C; Stk4; Mst1]
Gene, Accession #[Stk4], Gene ID: 58231, NCBI: NP_067395.1, UniProt: Q9JI11
Catalog #MBS9207416
Price$165, $370
Order / More InfoMouse Stk4 (C-term), 443-470 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesOh, H.J., et al. Curr. Biol. 20(5):416-422(2010) Lu, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1437-1442(2010) Song, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1431-1436(2010) Song, H., et al. Biochem. Biophys. Res. Commun. 391(1):969-973(2010) Choi, J., et al. PLoS ONE 4 (11), E8011 (2009) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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