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Antigenic Specificity | Mouse Stk4 (C-term), 443-470 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Stk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-470 amino acids from the C-terminal region of mouse Stk4. Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates a |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase 1; MST-1; STE20-like kinase MST1; Serine/threonine-protein kinase 4 37kDa subunit; MST1/N; Serine/threonine-protein kinase 4 18kDa subunit; MST1/C; Stk4; Mst1] |
Gene, Accession # | [Stk4], Gene ID: 58231, NCBI: NP_067395.1, UniProt: Q9JI11 |
Catalog # | MBS9207416 |
Price | $165, $370 |
Order / More Info | Mouse Stk4 (C-term), 443-470 Antibody from MYBIOSOURCE INC. |
Product Specific References | Oh, H.J., et al. Curr. Biol. 20(5):416-422(2010) Lu, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1437-1442(2010) Song, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1431-1436(2010) Song, H., et al. Biochem. Biophys. Res. Commun. 391(1):969-973(2010) Choi, J., et al. PLoS ONE 4 (11), E8011 (2009) : |