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Antigenic Specificity | beta Amyloid |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.46 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total beta Amyloid protein. This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 245 of beta Amyloid. |
Other Names | [AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN2; APP; alzheimer disease amyloid protein; beta-amyloid peptide; amyloid beta A4 protein; peptidase] |
Gene, Accession # | Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067 |
Catalog # | MBS9404410 |
Price | $320 |
Order / More Info | beta Amyloid Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |