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Antigenic Specificity | TIMP4 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, |
Immunogen | Immunogen: E Coli-derived human TIMP4 recombinant protein (Position: N174-P224). Human TIMP4 shares 92.2% amino acid (aa) sequence identity with both mouse and rat TIMP4. Subcellular Localization: Secreted. Tissue Specificity: Abundant in heart and present at low levels in many other tissues. |
Other Names | [Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4] |
Gene, Accession # | [TIMP4], Gene ID: 7079, NCBI: NP_003247.1, UniProt: Q99727 |
Catalog # | MBS1750919 |
Price | $315 |
Order / More Info | TIMP4 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |