Integrin alpha 6B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Integrin alpha 6B |
| Clone | [6B4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunocytochemistry (IHC), Immunohistochemistry (IHC) (frozen), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 6B4 recognizes specifically the cytoplasmic domain of integrin subunit alpha6B. 6B4 stains the basement membrane zone of ducts and acini of salivary gland, kidney tubules, epithelium of colonic crypts and weakly stains sweat glands and sebaceous glands. Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggre |
| Immunogen | Source Note: 6B4 is a Mouse monoclonal IgG1, kappa antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with a synthetic peptide corresponding to a 34 amino acid stretch in the cytoplasmic domain of integrin alpha6B including an appending N-terminal cysteine: CSRYDDSVPRYHAVRIRKEEREIKDEKYIDNLEKK coupled to keyhole limpet hemocyanin. |
| Other Names | [integrin alpha 6B; Integrin alpha-6; integrin alpha-6; integrin alpha6B; CD49 antigen-like family member F; integrin, alpha 6; CD49 antigen-like family member F; VLA-6], [ITGA6; ITGA6; CD49f; VLA-6; ITGA6B] |
| Gene, Accession # | Gene ID: 3655, NCBI: AAB20355.1, UniProt: P23229 |
| Catalog # | MBS570179 |
| Price | $415 |
| Order / More Info | Integrin alpha 6B Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hogervorst, F., Admiraal, L. G., Niessen, C., Kuikman, I., Janssen, H., Daams, H., and Sonnenberg, A. (1993). Biochemical characterization and tissue distribution of the A and B variants of the integrin alpha 6 subunit, J Cell Biol 121, 179-91. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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