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Antigenic Specificity | PKCtheta (Phospho-Ser676) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of PKCth only when phosphorylated at serine 676. This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 676 (R-L-S(p)-F-A) derived from Human PKCth. |
Other Names | [KPCT; PKC-theta; PKCQ; PRKCQ; PRKCT] |
Gene, Accession # | [PKCtheta], Gene ID: 5588, NCBI: NP_001229342.1, UniProt: Q04759 |
Catalog # | MBS9412877 |
Price | $200, $255 |
Order / More Info | PKCtheta (Phospho-Ser676) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |