Edit |   |
Antigenic Specificity | Mouse NKG2-A/C/E |
Clone | [20d5] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse NKG2 (Mr ~ 43 kDa). The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse CD94/NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa- 1b.2, 3 NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%). With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, |
Immunogen | Immunogen: CHO cells transfected with murine NKG2, 4 |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS673555 |
Price | $285 |
Order / More Info | Mouse NKG2-A/C/E Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Vance, R.E. and D.H. Raulet. Personal communication.2. Vance, R.E., J.R. Kraft, J.D. Altman, P.E. Jensen, and D.H. Raulet. 1998. J. Exp. Med. 188:1841.3. Kraft, J.R., Vance, R.E., J. Pohl, A.M. Martin, D.H. Raulet, and Jensen, P.E. 2000. J. Exp. Med. 192:613.4. Vance, R.E., A.M. Jamieson, and D.H. Raulet. 1999. J. Exp. Med. 190:1801. |