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Antigenic Specificity | Cish - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Cish. It was validated on Western BlotTarget Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Immunogen | Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse |
Other Names | [cytokine-inducible SH2-containing protein isoform 1; Cytokine-inducible SH2-containing protein; cytokine-inducible SH2-containing protein; cytokine inducible SH2-containing protein; CIS-1; Suppressor of cytokine signaling] |
Gene, Accession # | [CISH], Gene ID: 12700, NCBI: NP_034025, UniProt: Q62225 |
Catalog # | MBS3210984 |
Price | $365 |
Order / More Info | Cish - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |