Edit |   |
---|---|
Antigenic Specificity | LYN - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against LYN. It was validated on Western Blot using a cell lysate as a positive control.Target Description: LYN down regulates expression of stem cell growth factor receptor (KIT).LYN acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation.LYN acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. Involved in i |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LYN |
Other Names | [tyrosine-protein kinase Lyn isoform A; Tyrosine-protein kinase Lyn; tyrosine-protein kinase Lyn; LYN proto-oncogene, Src family tyrosine kinase; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn] |
Gene, Accession # | [LYN], Gene ID: 4067, NCBI: NP_002341, UniProt: P07948 |
Catalog # | MBS3211808 |
Price | $335 |
Order / More Info | LYN - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |