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Antigenic Specificity | Hsp70 (P.falciparum) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | It is species specific to P.falciparum and does nto cross-rect to any protein from human erythrocytes. |
Isotype | n/a |
Format | PerCP conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: This protein A Affinity purified antibody detects an 70kD protein, corresponding to P.falciparum Hsp70 on SDS PAGE immunoblot; in samples from P.Falciparum origin. Scientific Background: Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (1). The N-terminal two thirds of hsp70s are more conserved than the C-terminal third. Hsp70 binds ATP with high affinity and possesses a weak ATPase activity which c |
Immunogen | n/a |
Other Names | [HSP70_PLAFA; Cytoplasmic antigen 74.3 kDa protein; PfHsp70], [HSP70; HSP70] |
Gene, Accession # | NCBI: P11144.2, UniProt: P11144 |
Catalog # | MBS804972 |
Price | $435 |
Order / More Info | Hsp70 (P.falciparum) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Boorstein, W. R., Ziegelhoffer, T. & Craig, E. A. (1993), J. Mol. Evol.38 (1) 1-17. 2. Rothman, J. (1989), Cell 59, 591 -601. 3. DeLuca-Flaherty et al. (1990), Cell 62, 875-887. 4. Bork, P., Sander, C. & Valencia, A. (1992), Proc. Nut1 Acad. Sci. USA 89,7290-7294. 5. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 6. Pesce E.R., et al. (2008) Int J Biochem Cell Biol. 40(12):2914-26. 7. Pavithra S.R, Banumathy G., Joy O., Singh V., Tatu U. (2004) J Biol Chem. 279(45):46692-9 |