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Antigenic Specificity | Calmodulin-Dependent Protein Kinase II (CaMKII) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Immunoblot, Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes alpha, delta, and gamma isoforms of human, mouse, rat, bovine, hamster, guinea pig, chicken, and rabbit CaMKII. Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia. |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH. |
Other Names | [calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase type II subunit delta; calcium/calmodulin-dependent protein kinase type II subunit delta; calcium/calmodulin-dependent protein kinase II delta], [Camk2d; Camk2d; CAMK1; Camk2; Camki; RATCAMKI; CaM kinase II subunit delta; CaMK-II subunit delta] |
Gene, Accession # | [CaMKII], Gene ID: 24246, NCBI: NP_036651.1, UniProt: P15791 |
Catalog # | MBS191507 |
Price | $325, $545 |
Order / More Info | Calmodulin-Dependent Protein Kinase II (CaMKII) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |