Human VEGFR-2/KDR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman VEGFR-2/KDR
Clone[EIC]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.025 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionVEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
ImmunogenAntibody Generation: The monoclonal antibody was produced with the help of BALB/c mice using recombinant human soluble extracellular KDR (110 kDa) as the immunizing antigen. Mouse IgG1 antibody (clone KDR/EIC) from hybridomas was purified from cell culture supernatant by Protein G chromatography. Label: FITC Antigen: Recombinant Human soluble extracellular KDR (D7)
Other Names[Vascular endothelial growth factor receptor-2; KDR; FLK1; CD309; VEGF receptor 2; VEGFR2; Kinase insert domain protein receptor], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR]
Gene, Accession #[VEGFR-2/KDR -FITC], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968
Catalog #MBS692246
Price$250
Order / More InfoHuman VEGFR-2/KDR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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