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Antigenic Specificity | Human VEGFR-2/KDR |
Clone | [EIC] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
Immunogen | Antibody Generation: The monoclonal antibody was produced with the help of BALB/c mice using recombinant human soluble extracellular KDR (110 kDa) as the immunizing antigen. Mouse IgG1 antibody (clone KDR/EIC) from hybridomas was purified from cell culture supernatant by Protein G chromatography. Label: FITC Antigen: Recombinant Human soluble extracellular KDR (D7) |
Other Names | [Vascular endothelial growth factor receptor-2; KDR; FLK1; CD309; VEGF receptor 2; VEGFR2; Kinase insert domain protein receptor], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR] |
Gene, Accession # | [VEGFR-2/KDR -FITC], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS692246 |
Price | $250 |
Order / More Info | Human VEGFR-2/KDR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |