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Antigenic Specificity | RAF-1 (Phospho Ser338) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Raf-1 (S338) Polyclonal Antibody detects endogenous levels of Raf-1 protein only when phosphorylated at S338. RAF1 is the cellular homolog of viral raf gene (v-raf). Raf-1 proto-oncogene, serine/threonine kinase is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell divisi |
Immunogen | Immunogen: Synthesized peptide derived from human Raf-1 around the phosphorylation site of S338 |
Other Names | [Rabbit Raf-1 (phospho Ser338); RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1] |
Gene, Accession # | [RAF-1], Gene ID: 5894, NCBI: NP_002871.1, UniProt: P04049 |
Catalog # | MBS9701187 |
Price | $130, $220, $325 |
Order / More Info | RAF-1 (Phospho Ser338) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |