RAF-1 (Phospho Ser338) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAF-1 (Phospho Ser338)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phospho-Raf-1 (S338) Polyclonal Antibody detects endogenous levels of Raf-1 protein only when phosphorylated at S338. RAF1 is the cellular homolog of viral raf gene (v-raf). Raf-1 proto-oncogene, serine/threonine kinase is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell divisi
ImmunogenImmunogen: Synthesized peptide derived from human Raf-1 around the phosphorylation site of S338
Other Names[Rabbit Raf-1 (phospho Ser338); RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1]
Gene, Accession #[RAF-1], Gene ID: 5894, NCBI: NP_002871.1, UniProt: P04049
Catalog #MBS9701187
Price$130, $220, $325
Order / More InfoRAF-1 (Phospho Ser338) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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