KCNE1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-KCNE1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | KCNE1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Voltage-gated potassium channels play a variety of important roles in human health and disease (1, 2). KCNE1, also known as MinK, belongs to a family of small transmembrane proteins (KCNE1, 2, 3, 4, and KCNE1L) that modulate the activity of several voltage-gated K+ channels (3-5). KCNE1 functions as the modulatory beta-subunit of the pore-forming alpha-subunit KCNQ1, and alters several biophysical properties of KCNQ1 channels (6, 7). Research studies have shown that several inherited mutations in KCNE1 result in long QT syndrome (8-10) and deafness (11). |
| Immunogen | Immunogen: Recombinant protein of human KCNE1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [KCNE1; FLJ18426; FLJ38123; FLJ94103; ISK; JLNS; JLNS2; LQT2/5; LQT5; MGC33114; MinK] |
| Gene, Accession # | [KCNE1], Gene ID: 3753, NCBI: NP_000210.2, UniProt: P15382 |
| Catalog # | MBS8502062 |
| Price | $310 |
| Order / More Info | KCNE1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Jespersen, T. et al. (2005) Physiology (Bethesda) 20, 408-16. 2. Robbins, J. (2001) Pharmacol Ther 90, 1-19. 3. Takumi, T. et al. (1988) Science 242, 1042-5. 4. Abbott, G.W. and Goldstein, S.A. (2001) Mol Interv 1, 95-107. 5. McCrossan, Z.A. and Abbott, G.W. (2004) Neuropharmacology 47, 787-821. 6. Barhanin, J. et al. (1996) Nature 384, 78-80. 7. Sanguinetti, M.C. et al. (1996) Nature 384, 80-3. 8. Splawski, I. et al. (1997) Nat Genet 17, 338-40. 9. Abbott, G.W. and Goldstein, S.A. (2002) FASEB J 16, 390-400. 10. Tian, C. et al. (2007) Biochemistry 46, 11459-72. 11. Peters, T.A. et al. (2004) Pediatr Nephrol 19, 1194-201. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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