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Antigenic Specificity | BRD8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BRD8 Antibody detects endogenous levels of BRD8. Description: May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional progr |
Immunogen | Immunogen: A synthesized peptide derived from human BRD8. Tissue Specificity: Expressed in adipose tissue, brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. |
Other Names | [BRD8; Bromodomain containing 8; p120; Skeletal muscle abundant protein; Skeletal muscle abundant protein 2; SMAP; SMAP2; Thyroid hormone receptor coactivating protein 120kDa; Thyroid hormone receptor coactivating protein] |
Gene, Accession # | [BRD8], Gene ID: 10902, NCBI: Q9H0E9.2, UniProt: Q9H0E9 |
Catalog # | MBS9611609 |
Price | $240, $280 |
Order / More Info | BRD8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |