HP-1alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HP-1alpha |
| Clone | [6F1-10H3-6F5] |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when ' Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Immunogen | Immunogen: Purified recombinant protein expressed in E Coli. |
| Other Names | [Antigen p25; CBX5; HEL25; Heterochromatin protein 1; CBX5] |
| Gene, Accession # | [HP-1alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
| Catalog # | MBS8539861 |
| Price | $280 |
| Order / More Info | HP-1alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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