Human BACE1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human BACE1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human BACE1 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells. In the brain, This protein is expressed highly in the substantia nigra, locus coruleus and medulla oblongata. Strong BACE1 expression has also been described in pancreatic tissue. BACE1 has a pivotal role in the pathogenesis of Alzheimer's disease. In Alzheimer's disease patients, BACE1 levels were elevated although mRNA levels were not changed. It has been found that BACE1 gene expression is controlled by a TATA-less promoter. The translational repression as a new mechanism controlling its expression. And the low concentrations of Ca (2+) (microM range) significantly increased the proteolytic activity |
| Immunogen | Immunogen: Recombinant Human BACE1 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
| Other Names | [beta-secretase 1 isoform D; Beta-secretase 1; beta-secretase 1; beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2] |
| Gene, Accession # | [BACE1 ], Gene ID: 23621 |
| Catalog # | MBS2543827 |
| Price | $215, $330, $500 |
| Order / More Info | Human BACE1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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