AKT1 (Prognostic Marker for Neuroendocrine Tumors) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT1 (Prognostic Marker for Neuroendocrine Tumors)
Clone[AKT1/2784]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRecognizes a protein of 62kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.
ImmunogenImmunogen: Recombinant fragment of human AKT1 protein (around aa 85-189) (exact sequence is proprietary)
Other Names[AKT1; Oncogene AKT1; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Proto-oncogene c-Akt; RAC Alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha]
Gene, Accession #[AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749
Catalog #MBS4380872
Price$190, $340, $340
Order / More InfoAKT1 (Prognostic Marker for Neuroendocrine Tumors) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesFranke, T.F., et al. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81: 727-736.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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