Ep-CAM/CD326 (Extracellular Domain) (Epithelial Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEp-CAM/CD326 (Extracellular Domain) (Epithelial Marker)
Clone[Ber-EP4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatsupernatant
Size0.1 mL, 0.5 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionRecognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. It has been reported that this epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epi
ImmunogenImmunogen: Human breast cancer MCF-7 cells
Other Names[Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TACSTD1; TROP1; Tumor-associated Calcium Signal Transducer 1]
Gene, Accession #[Ep-CAM/CD326], Gene ID: 4072, NCBI: NP_002345.2, UniProt: P16422
Catalog #MBS4381070
Price$190, $340
Order / More InfoEp-CAM/CD326 (Extracellular Domain) (Epithelial Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLatza U, Niedobitek G, Schwarting R, Nekarda H, Stein H. Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelia. J Clin Pathol 1990;43:213-9.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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