IL2RB Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | IL2RB |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit beta(IL2RB) detection. Tested with WB in Mouse. Background: IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic dom |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB (503-539aa NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI), different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids. Ig Type: Rabbit IgG |
| Other Names | [Interleukin-2 receptor subunit beta; CD 122; CD122; CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; High affinity IL-2 receptor subunit beta; High affinity IL2 receptor beta subunit; High affinity IL2 receptor subunit beta; IL 2 receptor; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; IL15RB; IL2 R B; IL2 RB; IL2 receptor; IL2RB; IL2RB_HUMAN; Interleukin 2 receptor beta; Interleukin 2 receptor subunit beta; Interleukin-2 receptor subunit beta; OTTHUMP00000028799; P70 75; P70-75; P7075; p75; interleukin 2 receptor, beta], [Il2rb; Il2rb; p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB] |
| Gene, Accession # | [IL2RB], Gene ID: 16185, NCBI: NP_032394.1, UniProt: P16297 |
| Catalog # | MBS178267 |
| Price | $280 |
| Order / More Info | IL2RB Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Campbell, H. D., Webb, G. C., Kono, T., Taniguchi, T., Ford, J. H., Young, I. G. Assignment of the interleukin-2 receptor beta chain gene (Il-2rb) to band E on mouse chromosome 15. Genomics 12: 179-180, 1992. 2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8 CD122 T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010. 3. Yamashita, Yuki; Kojima Katsuhiko, Tsukahara Tomonori, Agawa Hideyuki, Yamada Koichiro, Amano Yuji, Kurotori Naoki, Tanaka Nobuyuki, Sugamura Kazuo, Takeshita Toshikazu (May. 2008). Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain. J. Cell. Sci. (England) 121 (Pt 10): 1727-38. doi:10.1242/jcs.024455. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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