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Antigenic Specificity | NRG1 isoform-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NRG1 isoform-10 protein. The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).Xiao-Feng Le, Cancer Res., Jul 2000; 60: 3522 - 3531.Samuel D. H. Chan, J. Biol. Chem., Sep 1995; 270: |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human NRG1 isoform-10. |
Other Names | [Pro-neuregulin-1; membrane-bound isoform; Pro-NRG1; NRG1; GGF] |
Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q15491 |
Catalog # | MBS9407959 |
Price | $200, $255 |
Order / More Info | NRG1 isoform-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |