TIMP3 Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTIMP3 Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
ConcentrationAdd 0.2ml of distilled water will yield a concentration of 500ug/ml.
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionDescription: Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. It is mapped to 22q12.1-q13.2. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of theextracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding t
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence in the middle region of human TIMP3 (107-141aa RVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHL), different from the related mouse and rat sequences by two amino acids. Subcellular Localization: Secreted, extracellular space, extracellular matrix.
Other Names[Metalloproteinase inhibitor 3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP-3; TIMP3]
Gene, Accession #[TIMP3], Gene ID: 7078, NCBI: NP_000353.1, UniProt: P35625
Catalog #MBS1750417
Price$280
Order / More InfoTIMP3 Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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