Phospho-CDH1 (Tyr754) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CDH1 (Tyr754)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-CDH1 (Tyr754) Antibody detects endogenous levels of CDH1 only when phosphorylated at Tyr754. Description: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.Post Translational Modifications: During apoptosis or with calcium influx, cleaved by a membrane-bound metalloproteinase (ADAM10), PS1/gamma-secretase and caspase-3 to
ImmunogenImmunogen: A synthesized peptide derived from human CDH1 around the phosphorylation site of Tyr754. Tissue Specificity: Non-neural epithelial tissues.
Other Names[Arc 1; CADH1_HUMAN; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin]
Gene, Accession #[CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830
Catalog #MBS9610580
Price$225, $280, $340
Order / More InfoPhospho-CDH1 (Tyr754) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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