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Antigenic Specificity | Phospho-CDH1 (Tyr754) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CDH1 (Tyr754) Antibody detects endogenous levels of CDH1 only when phosphorylated at Tyr754. Description: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.Post Translational Modifications: During apoptosis or with calcium influx, cleaved by a membrane-bound metalloproteinase (ADAM10), PS1/gamma-secretase and caspase-3 to |
Immunogen | Immunogen: A synthesized peptide derived from human CDH1 around the phosphorylation site of Tyr754. Tissue Specificity: Non-neural epithelial tissues. |
Other Names | [Arc 1; CADH1_HUMAN; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin] |
Gene, Accession # | [CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830 |
Catalog # | MBS9610580 |
Price | $225, $280, $340 |
Order / More Info | Phospho-CDH1 (Tyr754) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |